-
1.发明公开COMPOUNDS ANALOGOUS TO GROWTH HORMONE PEPTIDE SECRETAGOGUES AND PREPARATIONS CONTAINING THEM 有权与生长激素肽类似物相容的化合物以及含有它们的制剂
公开(公告)号：EP1997827A1
公开(公告)日：2008-12-03
申请号：EP07711101.1
申请日：2007-02-28
发明人： RODRIGUEZ FERNANDEZ, Rolando, Eduardo , DE LA NUEZ VEULENS, Ania , ESTRADA GARCÍA, Mario, Pablo , MARTÍNEZ RODRÍGUEZ, Rebeca , CHINEA SANTIAGO, Glay , REYES ACOSTA, Osvaldo , FERNÁNDEZ MASSÓ, Julio, Raúl , GARCÍA DEL BARCO HERRERA, Diana , BERLANGA ACOSTA, Jorge, Amador , MUSACCHIO LASA, Alexis
摘要： Peptidic chemical compounds obtained by in silico molecular modelling, having a structure that enables them to perform the same functions of peptidic growth hormone secretagogues. The invention also comprises the preparations containing such compounds and the use in medicines, food additives, nutritional supplements or other formulations of human or animal use.
摘要翻译： 通过计算机模拟分子模型获得的肽化学化合物，具有使它们能够执行肽生长激素促分泌素相同功能的结构。 本发明还包括含有这些化合物的制剂以及在药物，食品添加剂，营养增补剂或其它人或动物用途制剂中的用途。
-
公开(公告)号：EP1892245A2
公开(公告)日：2008-02-27
申请号：EP06753157.4
申请日：2006-05-05
发明人： RODRIGUEZ FERNANDEZ, Rolando Eduardo , VERA ALVAREZ, Roberto , DE LA NUEZ VEULENS, Ania , MAZOLA REYES, Yuliet , PEREA RODRÍGUEZ, Silvio, Ernesto , ACEVEDO CASTRO, Boris Ernesto , MUSACCHIO LASA, Alexis , UBIETA GÓMEZ, Raimundo
IPC分类号： C07F9/22 , C07D487/04 , C07D239/42 , C07D239/36 , C07D233/54 , C07D235/14 , C07D215/18 , C07D213/82 , C07D207/36 , C07C237/30 , C07C327/44 , C07C313/06 , C07C275/36 , C07C275/22 , C07C275/18
CPC分类号： C07C211/14 , C07C237/06 , C07C237/22 , C07C243/28 , C07C255/42 , C07C257/14 , C07C271/22 , C07C271/64 , C07C275/08 , C07C275/16 , C07C275/24 , C07C281/12 , C07C317/28 , C07C327/42 , C07C337/08 , C07D207/34 , C07D209/14 , C07D213/81 , C07D213/82 , C07D215/46 , C07D233/88 , C07D233/91 , C07D235/14 , C07D239/36 , C07D239/46 , C07D239/54 , C07D251/22 , C07D307/52 , C07D487/04 , C07F9/224
摘要： Chemical compounds identified by in silico molecular modelling, and having an structure that allows the blocking of the phosphorylation event, through the interaction of such compounds with the phosphorylation domain or its milieu in the substrates of the Casein Kinase 2 enzyme. This invention comprises also the pharmaceutical compositions containing such compounds, and their use in the preparation of medicines for the treatment of diseases related with neoplasic processes.
摘要翻译： 化学化合物通过硅胶分子模拟鉴定，并具有允许阻断磷酸化事件的结构，通过这些化合物与酪蛋白激酶2酶底物中磷酸化结构域或其环境的相互作用。 本发明还包含含有这些化合物的药物组合物及其在制备用于治疗与新生物相关疾病的药物中的用途。
-
公开(公告)号：EP1892245B1
公开(公告)日：2015-07-29
申请号：EP06753157.4
申请日：2006-05-05
发明人： RODRIGUEZ FERNANDEZ, Rolando Eduardo , VERA ALVAREZ, Roberto , DE LA NUEZ VEULENS, Ania , MAZOLA REYES, Yuliet , PEREA RODRÍGUEZ, Silvio, Ernesto , ACEVEDO CASTRO, Boris Ernesto , MUSACCHIO LASA, Alexis , UBIETA GÓMEZ, Raimundo
IPC分类号： C07F9/22 , C07D487/04 , C07D239/42 , C07D239/36 , C07D233/54 , C07D235/14 , C07D215/18 , C07D213/82 , C07D207/36 , C07C237/30 , C07C327/44 , C07C313/06 , C07C275/36 , C07C275/22 , C07C275/18
CPC分类号： C07C211/14 , C07C237/06 , C07C237/22 , C07C243/28 , C07C255/42 , C07C257/14 , C07C271/22 , C07C271/64 , C07C275/08 , C07C275/16 , C07C275/24 , C07C281/12 , C07C317/28 , C07C327/42 , C07C337/08 , C07D207/34 , C07D209/14 , C07D213/81 , C07D213/82 , C07D215/46 , C07D233/88 , C07D233/91 , C07D235/14 , C07D239/36 , C07D239/46 , C07D239/54 , C07D251/22 , C07D307/52 , C07D487/04 , C07F9/224
-
4.发明授权COMPOUNDS ANALOGOUS TO GROWTH HORMONE PEPTIDE SECRETAGOGUES AND PREPARATIONS CONTAINING THEM 有权与生长激素肽类似物相容的化合物以及含有它们的制剂
公开(公告)号：EP1997827B1
公开(公告)日：2013-10-09
申请号：EP07711101.1
申请日：2007-02-28
发明人： RODRIGUEZ FERNANDEZ, Rolando, Eduardo , DE LA NUEZ VEULENS, Ania , ESTRADA GARCÍA, Mario, Pablo , MARTÍNEZ RODRÍGUEZ, Rebeca , CHINEA SANTIAGO, Glay , REYES ACOSTA, Osvaldo , FERNÁNDEZ MASSÓ, Julio, Raúl , GARCÍA DEL BARCO HERRERA, Diana , BERLANGA ACOSTA, Jorge, Amador , MUSACCHIO LASA, Alexis
-
-
-
搜索结果
4 条记录 (耗时 0.011 秒)
