发明公开
EP1907016A2 METHODS AND COMPOSITION FOR MODULATING FOXO1 ACTIVITY AND INSULIN SIGNALING
审中-公开
方法和组合物调制FOXO1活动与胰岛素信号
- 专利标题： METHODS AND COMPOSITION FOR MODULATING FOXO1 ACTIVITY AND INSULIN SIGNALING
- 专利标题（中）： 方法和组合物调制FOXO1活动与胰岛素信号
-
申请号： EP06787013.9申请日： 2006-07-11
-
公开(公告)号： EP1907016A2公开(公告)日： 2008-04-09
- 发明人: CHO, Charles , CHANDA, Sumit , SCHULTZ, Peter G.
- 申请人： IRM, LLC
- 申请人地址： Hurst Holme 12 Trott Road Hamilton, HM 11 BM
- 专利权人： IRM, LLC
- 当前专利权人： IRM, LLC
- 当前专利权人地址： Hurst Holme 12 Trott Road Hamilton, HM 11 BM
- 代理机构： Kiddle, Simon John
- 优先权： US698322P 20050711
- 国际公布： WO2007008982 20070118
- 主分类号： A61K48/00
- IPC分类号： A61K48/00 ; C12N15/11
摘要：
The invention provides methods for modulating insulin signaling pathway and methods for treating insulin resistance. The methods employ agents which modulate FOXO1 subcellular localization. The invention also provides methods of screening for compounds that modulate insulin signaling related activities such as gluconeogenesis and cell proliferation.
信息查询
