发明公开
- 专利标题: IMPROVED PROTEIN EXPRESSION
- 专利标题(中): 改进的蛋白质表达
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申请号: EP05762730.9申请日: 2005-07-29
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公开(公告)号: EP1913143A1公开(公告)日: 2008-04-23
- 发明人: KJÆRULFF, Søren
- 申请人: Pharmexa A/S
- 申请人地址: Kogle Allé 6 2970 Horsholm DK
- 专利权人: Pharmexa A/S
- 当前专利权人: Pharmexa A/S
- 当前专利权人地址: Kogle Allé 6 2970 Horsholm DK
- 代理机构: Inspicos A/S
- 国际公布: WO2007012334 20070201
- 主分类号: C12N15/62
- IPC分类号: C12N15/62 ; C12N15/81
摘要:
Disclosed is chimeric polynucleotides adopted for providing high-yield expression and secretion of recombinant polypeptides. The chimeric polynucleotide of the invention includes a functional secretion signal peptide derived from S. pombe carboxypeptidase Y (CPY). The invention also discloses methods for use of this cpy leader sequence.
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