发明公开
EP1917050A2 HYDROGEL BALLOON PROSTHESIS FOR NUCLEUS PULPOSUS
有权
HYDROGEL-BALLONPROTHESEFÜRNUCLEUS PULPOSUS
- 专利标题: HYDROGEL BALLOON PROSTHESIS FOR NUCLEUS PULPOSUS
- 专利标题(中): HYDROGEL-BALLONPROTHESEFÜRNUCLEUS PULPOSUS
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申请号: EP06813765.2申请日: 2006-08-25
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公开(公告)号: EP1917050A2公开(公告)日: 2008-05-07
- 发明人: MARCOLONGO, Michele, S. , LOWMAN, Anthony, M. , CLEMOW, Alastair, J., T. , KEANE, Michael, F. , VRESILOVIC, Edward
- 申请人: Synthes GmbH
- 申请人地址: Eimattstrasse 3 4436 Oberdorf CH
- 专利权人: Synthes GmbH
- 当前专利权人: Synthes GmbH
- 当前专利权人地址: Eimattstrasse 3 4436 Oberdorf CH
- 代理机构: Lusuardi, Werther
- 优先权: US711430P 20050826
- 国际公布: WO2007025164 20070301
- 主分类号: A61L27/52
- IPC分类号: A61L27/52 ; A61F2/44
摘要:
A prosthesis for replacing or supplementing a nucleus pulposus of an intervertebral disk is an expandable container having flexible walls, the container being adapted to be inserted into a central cavity of an intervertebral disk through a narrow cannula, and the flexible walls are made from a biocompatible hydrogel. A preferred hydrogel is a cryogel formed from an aqueous solution of poly(vinyl alcohol) and poly(vinyl pyrrolidone). The prosthesis may be prepared by dip-coating a mandrel with an aqueous solution of a hydrogel-forming polymer or mixture of such polymers, gelling the coated solution by chilling, and subjecting the gelled coating to a series of repeated freeze-thaw treatments. In use, the prosthesis is inserted into a central cavity of an intervertebral disk and filled with biocompatible material, e.g., a biocompatible liquid, a biocompatible polymer, and a biocompatible hydrogel, particularly a thermogelling hydrogel.
公开/授权文献
- EP1917050B1 HYDROGEL BALLOON PROSTHESIS FOR NUCLEUS PULPOSUS 公开/授权日:2010-04-14
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