利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

1591 条记录 (耗时 0.02 秒)

    SOL-GEL TRANSITION OF 6-ARM PEG HYDROGEL OVER TIME
    6.
    发明公开
    SOL-GEL TRANSITION OF 6-ARM PEG HYDROGEL OVER TIME 审中-实审

    公开(公告)号：EP4400125A1

    公开(公告)日：2024-07-17

    申请号：EP22867731.6

    申请日：2022-09-08

    申请人： Sunbio Inc.

    发明人： HWANG, Seongu ,  KIM, Ga Eun

    IPC分类号： A61L27/52 ,  A61L27/18 ,  A61B17/56

    CPC分类号： A61B17/56 ,  A61L27/52 ,  A61L27/18

    摘要： The present invention relates to a 6-arm PEG hydrogel composition whose physical properties are converted from a sol to a gel within 30 minutes over time.
    In the present invention, two types of PEG derivatives are included as a main component of the hydrogel, and when each of the PEG derivatives is dissolved in a buffer solution, and then the two solutions are mixed, it can be converted in physical properties to a gel state within 30 minutes.

    BIONIC CORNEA AND PREPARATION METHOD THEREFOR
    8.
    发明公开
    BIONIC CORNEA AND PREPARATION METHOD THEREFOR 审中-实审

    公开(公告)号：EP4393521A1

    公开(公告)日：2024-07-03

    申请号：EP22866196.3

    申请日：2022-06-20

    申请人： Eosvision Medtech Technology Co., Ltd.

    发明人： WANG, Chongyu ,  ZHANG, Jiahui ,  ZHANG, Jun ,  LIU, Murong ,  HE, Chaoxian

    IPC分类号： A61L27/24 ,  A61L27/50 ,  A61L27/52 ,  C07K14/00

    摘要： The present application relates to the field of biotechnology, and relates to a bionic cornea and a preparation method therefor. The present application provides a bionic cornea. A raw material of the bionic cornea is pegylated collagen. The pegylated collagen comprises collagen and PEG-40k and PEG-20k which are modified on the collagen. Modifications of PEG-40k and PEG-20k can significantly improve the cross-linking performance of the collagen, so that the strength of the cornea of the present application is increased by nearly 20 times compared with the strength of the cornea prepared from collagen, and is increased by nearly 12 times compared with the strength of the cornea prepared from the existing another pegylated collagen. Therefore, the cornea of the present application has good application prospect in the field of corneal transplantation. A molar ratio of PEG-40k to PEG-20k is 2-3:1. The effect of improving the cross-linking performance of the collagen by PEG modification at this molar ratio is better, and the strength of the cornea of the present application can be further improved.