发明公开
- 专利标题： BICYCLISCHE HETEROCYCLEN, DIESE VERBINDUNGEN ENTHALTENDE ARZNEIMITTEL, DEREN VERWENDUNG UND VERFAHREN ZU IHRER HERSTELLUNG
- 专利标题（英）： Bicyclic heterocycles medicaments comprising said compounds use and method for production thereof
- 专利标题（中）： 双环杂环，药物含有它们，它们的使用和工艺及其
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申请号： EP06778135.1申请日： 2006-08-03
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公开(公告)号： EP1919900A2公开(公告)日： 2008-05-14
- 发明人: HIMMELSBACH, Frank , JUNG, Birgit
- 申请人： BOEHRINGER INGELHEIM INTERNATIONAL GMBH , Boehringer Ingelheim Pharma GmbH & Co. KG
- 申请人地址： Binger Str. 173 D-55216 Ingelheim DE
- 专利权人： BOEHRINGER INGELHEIM INTERNATIONAL GMBH,Boehringer Ingelheim Pharma GmbH & Co. KG
- 当前专利权人： BOEHRINGER INGELHEIM INTERNATIONAL GMBH,Boehringer Ingelheim Pharma GmbH & Co. KG
- 当前专利权人地址： Binger Str. 173 D-55216 Ingelheim DE
- 代理机构： Hammann, Heinz
- 优先权： EP05107679 20050822
- 国际公布： WO2007023073 20070301
- 主分类号： C07D401/12
- IPC分类号： C07D401/12 ; C07D403/12 ; C07D239/94 ; A61K31/517
摘要：
The invention relates to bicyclic heterocycles of general formula (I), in which Ra, Rb, Rc, Rd, Re and X are as defined in claim 1, the tautomers, stereoisomers, mixtures and salts thereof, in particular, the physiologically-acceptable salts thereof with inorganic and organic acids with useful pharmacological properties, in particular, an inhibitory effect on signal transduction brought about by tyrosine kinases, the use thereof for the treatment of diseases, in particular of tumour diseases and benign prostatic hyperplasia (BPH), diseases of the lungs and airways and production thereof.
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