发明公开
EP1930025A1 ANTIGEN-AND-DRUG VEHICLE WHICH ENABLES THE CHANGEOVER FROM THE SELECTIVE PRODUCTION OF IgA ANTIBODY TO THE PRODUCTION OF BOTH OF IgA AND IgG ANTIBODIES, AND TRANSNASAL/TRANSMUCOSAL VACCINE USING THE VEHICLE
有权
抗原和药物车辆ENABLE IgA抗体的选择性生产转化成的IgA和IgG抗体和经鼻/粘膜疫苗本车辆上的生产
- 专利标题: ANTIGEN-AND-DRUG VEHICLE WHICH ENABLES THE CHANGEOVER FROM THE SELECTIVE PRODUCTION OF IgA ANTIBODY TO THE PRODUCTION OF BOTH OF IgA AND IgG ANTIBODIES, AND TRANSNASAL/TRANSMUCOSAL VACCINE USING THE VEHICLE
- 专利标题(中): 抗原和药物车辆ENABLE IgA抗体的选择性生产转化成的IgA和IgG抗体和经鼻/粘膜疫苗本车辆上的生产
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申请号: EP06782373.2申请日: 2006-08-04
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公开(公告)号: EP1930025A1公开(公告)日: 2008-06-11
- 发明人: KIDO, Hiroshi , MIZUNO, Dai
- 申请人: The University of Tokushima
- 申请人地址: 24, Shinkura-cho 2-chome Tokushima-shi, Tokushima 770-8501 JP
- 专利权人: The University of Tokushima
- 当前专利权人: The University of Tokushima
- 当前专利权人地址: 24, Shinkura-cho 2-chome Tokushima-shi, Tokushima 770-8501 JP
- 代理机构: Owen, Deborah Jane
- 优先权: JP2005227504 20050805
- 国际公布: WO2007018152 20070215
- 主分类号: A61K39/00
- IPC分类号: A61K39/00 ; A61P37/08
摘要:
In the aim of practical utilization of a safe and effective transnasal/inactivated/mucosal vaccine and establishment of a technology for imparting capacity of producing both of IgA and IgG antibodies to a conventional inactivated vaccine, toxoid, allergen, or the like, a means for prevention and treatment of allergy, and the like, it is intended to provide an antigen-drug vehicle (AD vehicle) enabling transnasal, transmucosal, and transdermal administrations, an inactivated vaccine simultaneously inducing a mucosal immunity and humoral immunity by using the AD vehicle, a production method of the inactivated vaccine, an AD vehicle enabling a switch from induction of selective production of IgA antibody to induction of both of IgA and IgG antibodies, and a transnasal vaccine, a mucosal vaccine, a therapeutic/prophylactic agent for allergy, and the like using the AD vehicle.
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