发明授权
EP1930416B1 NOVEL RECOMBINANT HUMAN HEPATITIS C VIRUS-LIKE PARTICLE AND METHOD FOR PRODUCING THE SAME
有权
与函电人类丙型肝炎病毒和方法及其制造新型重组粒子
- 专利标题： NOVEL RECOMBINANT HUMAN HEPATITIS C VIRUS-LIKE PARTICLE AND METHOD FOR PRODUCING THE SAME
- 专利标题（中）： 与函电人类丙型肝炎病毒和方法及其制造新型重组粒子
-
申请号： EP06810937.0申请日： 2006-09-29
-
公开(公告)号： EP1930416B1公开(公告)日： 2011-12-14
- 发明人: TANABE, Jun-ichi, c/o Pharmaceutical Research Laboratories , SONE, Saburo , WAKITA, Takaji, c/o Department of Virology II, National Institute , ISHII, Koji , SUZUKI, Ryosuke , SUZUKI, Tetsuro , MIYAMURA, Tatsuo
- 申请人： JAPAN AS REPRESENTED BY THE DIRECTOR-GENERAL OF NATIONAL INSTITUTE OF INFECTIOUS DISEASES , Tokyo Metropolitan Institute of Medical Science , TORAY INDUSTRIES, INC.
- 申请人地址： 23-1, Toyama 1-chome Shinjuku-ku Tokyo 162-8640 JP
- 专利权人： JAPAN AS REPRESENTED BY THE DIRECTOR-GENERAL OF NATIONAL INSTITUTE OF INFECTIOUS DISEASES,Tokyo Metropolitan Institute of Medical Science,TORAY INDUSTRIES, INC.
- 当前专利权人： JAPAN AS REPRESENTED BY THE DIRECTOR-GENERAL OF NATIONAL INSTITUTE OF INFECTIOUS DISEASES,Tokyo Metropolitan Institute of Medical Science,TORAY INDUSTRIES, INC.
- 当前专利权人地址： 23-1, Toyama 1-chome Shinjuku-ku Tokyo 162-8640 JP
- 代理机构： Kador & Partner
- 优先权： JP2005287825 20050930
- 国际公布： WO2007037429 20070405
- 主分类号： C12N7/00
- IPC分类号： C12N7/00 ; C12N15/09 ; C12N7/04
摘要：
The invention relates to a method for producing a recombinant hepatitis C virus-like particle comprising introducing into (i) a cell which autonomously replicates an RNA replicon including a base sequence encoding a 5’ noncoding region, NS3 protein, NS4A protein, NS4B protein, NS5A protein and NS5B protein in the genomic RNA derived from a hepatitis C virus strain and a base sequence including a 3’ noncoding region, (ii) a vector expressing Core protein, E1 protein, E2 protein and p7 protein derived from the same or a different hepatitis C virus strain in (i), culturing the cell and collecting the produced virus-like particle and a recombinant hepatitis C virus particle produced by the method.
公开/授权文献
信息查询
