发明公开
- 专利标题: INDOL-3-YL-CARBONYL-AZASPIRO DERIVATIVES AS VASOPRESSIN RECEPTOR ANTAGONISTS
- 专利标题(中): 吲哚-3-乙酰胆碱酯酶抑制剂
-
申请号: EP06793584.1申请日: 2006-09-18
-
公开(公告)号: EP1931680A1公开(公告)日: 2008-06-18
- 发明人: BISSANTZ, Caterina , GRUNDSCHOBER, Christophe , RATNI, Hasane , ROGERS-EVANS, Mark , SCHNIDER, Patrick
- 申请人: F.HOFFMANN-LA ROCHE AG
- 申请人地址: Grenzacherstrasse 124 4070 Basel CH
- 专利权人: F.HOFFMANN-LA ROCHE AG
- 当前专利权人: F.HOFFMANN-LA ROCHE AG
- 当前专利权人地址: Grenzacherstrasse 124 4070 Basel CH
- 代理机构: Wasner, Marita
- 优先权: EP05108966 20050928
- 国际公布: WO2007039438 20070412
- 主分类号: C07D491/10
- IPC分类号: C07D491/10 ; C07D471/10 ; A61K31/4355 ; A61K31/437 ; A61P9/00 ; A61P25/00
摘要:
This invention relates to indol-3-yl-carbonyl-azaspiro derivatives which act as Via receptor antagonists and which are represented by Formula (I) wherein the azaspiro-head group A and the residues R1, R2 and R3 are as defined herein. The invention further relates to pharmaceutical compositions containing such compounds, their use in medicaments against dysmenorrhea, hypertension, chronic heart failure, inappropriate secretion of vasopressin, liver cirrhosis, nephrotic syndrome, obsessive compulsive disorder, anxiety and depressive disorders, and methods of preparation thereof.
公开/授权文献
信息查询