发明授权
- 专利标题： PRODUCTION AND PURIFICATION OF IL-29
- 专利标题（中）： 生产和清洁IL-29
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申请号： EP06816409.4申请日： 2006-10-04
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公开(公告)号： EP1931704B1公开(公告)日： 2010-12-15
- 发明人: ZAMOST, Bruce, L. , LEE, Geoffrey, F. , DEDINSKY, Robert, M.
- 申请人： ZymoGenetics, L.L.C. , Bristol-Myers Squibb Company
- 申请人地址： 1201 Eastlake Avenue East Seattle, WA 98102 US
- 专利权人： ZymoGenetics, L.L.C.,Bristol-Myers Squibb Company
- 当前专利权人： ZymoGenetics, L.L.C.,Bristol-Myers Squibb Company
- 当前专利权人地址： 1201 Eastlake Avenue East Seattle, WA 98102 US
- 代理机构： MacLean, Martin Robert
- 优先权： US723544P 20051004
- 国际公布： WO2007041713 20070412
- 主分类号： C07K14/54
- IPC分类号： C07K14/54
摘要：
The expression vectors and methods using an E. coli expression system for the large scale production of IL-29 are described. The vectors utilize the IL-29 coding sequence with specific changes in nucleotides in order to optimize codons and mRNA secondary structure for translation in E. coli. Also included are methods of producing, purifying and pegylating an IL-29 polypeptide.
公开/授权文献
- EP1931704A1 PRODUCTION AND PURIFICATION OF IL-29 公开/授权日：2008-06-18
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