发明公开
- 专利标题： STABILIZED EXTENDED RELEASE PHARMACEUTICAL COMPOSITIONS COMPRISING A BETA-ADRENORECEPTOR ANTAGONIST
- 专利标题（中）： 来稳定的β阻断拮抗剂缓释药物组合物的
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申请号： EP06790888.9申请日： 2006-10-24
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公开(公告)号： EP1945197A1公开(公告)日： 2008-07-23
- 发明人: JOSHI, Laxminarayan , LEFLER, Robert, Scott
- 申请人： Orbus Pharma Inc.
- 申请人地址： 20 Konrad Crescent Markham, ON L3R 8T4 CA
- 专利权人： Orbus Pharma Inc.
- 当前专利权人： Orbus Pharma Inc.
- 当前专利权人地址： 20 Konrad Crescent Markham, ON L3R 8T4 CA
- 代理机构： Vogel, Andreas
- 优先权： US257526 20051024; US551865 20061023
- 国际公布： WO2007048233 20070503
- 主分类号： A61K31/138
- IPC分类号： A61K31/138 ; A61K47/30 ; A61K9/28
摘要：
The present invention is a new stable extended release drug composition particularly suitable for use as a beta-adrenoreceptor antagonist agent. The present invention is specifically a drug composition comprising a pharmaceutical, a methacrylic acid copolymer and a matrix forming agent, and a method for manufacturing same. When applied to highly soluble drugs like metoprolol succinate, the resulting drug composition is characterized by an extended-release profile.
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