发明公开
EP1955703A1 Viruses for the treatment of cellular proliferative disorders
审中-公开
Virenfürdie Behandlung vonzellulären,proliferativen Erkrankungen
- 专利标题: Viruses for the treatment of cellular proliferative disorders
- 专利标题(中): Virenfürdie Behandlung vonzellulären,proliferativen Erkrankungen
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申请号: EP08009283.6申请日: 2000-11-08
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公开(公告)号: EP1955703A1公开(公告)日: 2008-08-13
- 发明人: Coffey, Matthew C. , Thompson, Bradley G.
- 申请人: Oncolytics Biotech Inc.
- 申请人地址: Suite 210 1167 Kensington Crescent N. W. Calgary, AB T2N 1X7 CA
- 专利权人: Oncolytics Biotech Inc.
- 当前专利权人: Oncolytics Biotech Inc.
- 当前专利权人地址: Suite 210 1167 Kensington Crescent N. W. Calgary, AB T2N 1X7 CA
- 代理机构: Vossius & Partner
- 优先权: US164878P 19991112
- 主分类号: A61K35/76
- IPC分类号: A61K35/76 ; A61P35/00
摘要:
Methods for treating cell proliferative disorders by administering virus to proliferative cells having an activated Ras-pathway are disclosed. The virus is administered so that it ultimately directly contacts proliferating cells having an activated Ras-pathway. Proliferative disorders include but are not limited to neoplasms. The virus is selected form modified adenovirus, modified HSV, modified vaccinia virus and modified parapoxvirus orf virus. Also disclosed are methods for treating cell proliferative disorders by further administering an immunosuppressive agent.
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