发明公开
- 专利标题: MEDICINAL DRUG
- 专利标题(中): 医疗药品
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申请号: EP06834365.6申请日: 2006-12-04
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公开(公告)号: EP1957073A2公开(公告)日: 2008-08-20
- 发明人: MATSUYAMA, Hironori , OHNISHI, Kenji , NAKAGAWA, Takashi , TAKASU, Hideki , SAKAMOTO, Makoto , HIGUCHI, Kumi , MIYAJIMA, Keisuke , YAMADA, Satoshi , MOTOYAMA, Masaaki , KOJIMA, Yutaka , YASUMURA, Koichi , KODAMA, Takeshi , OTSUJI, Shun , KAN, Keizo , SUMIDA, Takumi
- 申请人: OTSUKA PHARMACEUTICAL CO., LTD.
- 申请人地址: 9, Kanda-Tsukasacho 2-chome, Chiyoda-ku Tokyo 101-8535 JP
- 专利权人: OTSUKA PHARMACEUTICAL CO., LTD.
- 当前专利权人: OTSUKA PHARMACEUTICAL CO., LTD.
- 当前专利权人地址: 9, Kanda-Tsukasacho 2-chome, Chiyoda-ku Tokyo 101-8535 JP
- 代理机构: HOFFMANN EITLE
- 优先权: JP2005351255 20051205
- 国际公布: WO2007066784 20070614
- 主分类号: A61K31/495
- IPC分类号: A61K31/495 ; A61K31/496 ; A61P35/00
摘要:
An object of the present invention is to provide a medicinal drug much improved in anti tumor activity and excellent in safety. According to the present invention, there is provided a medicinal drug containing a compound represented by the following general formula (1) or a salt thereof as an active ingredient: [Formula 1] wherein X1 represents a nitrogen atom or a group -CH=, R1 represents a group -Z-R6, in which Z represents a group -CO-, a group -CH(OH)- or the like, R6 represents a 5- to 15-membered monocyclic, dicyclic or tricyclic saturated or unsaturated heterocyclic group having 1 to 4 nitrogen atoms, oxygen atoms or sulfur atoms, R2 represents a hydrogen atom or a halogen atom, Y represents a group -O-, a group -CO-, a group -CH(OH)- or a lower alkylene group, and A represents [Formula 2] wherein R3 represents a hydrogen atom, a lower alkoxy group or the like, p represents 1 or 2, R4 represents an imidazolyl lower alkyl group or the like.
公开/授权文献
- EP1957073B1 MEDICINAL DRUG 公开/授权日:2014-04-23
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