发明公开
EP1959961A2 FORMULATION OF INSOLUBLE SMALL MOLECULE THERAPEUTICS IN LIPID-BASED CARRIERS
审中-公开
配方介质中不溶，小分子剂对基于脂肪的
- 专利标题： FORMULATION OF INSOLUBLE SMALL MOLECULE THERAPEUTICS IN LIPID-BASED CARRIERS
- 专利标题（中）： 配方介质中不溶，小分子剂对基于脂肪的
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申请号： EP06850222.8申请日： 2006-12-01
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公开(公告)号： EP1959961A2公开(公告)日： 2008-08-27
- 发明人: PARMAR, Manjeet M.
- 申请人： Rigel Pharmaceuticals, Inc.
- 申请人地址： 1180 Veterans Boulevard South San Francisco, CA 94080 US
- 专利权人： Rigel Pharmaceuticals, Inc.
- 当前专利权人： Rigel Pharmaceuticals, Inc.
- 当前专利权人地址： 1180 Veterans Boulevard South San Francisco, CA 94080 US
- 代理机构： Sexton, Jane Helen
- 优先权： US742954P 20051206
- 国际公布： WO2007111720 20071004
- 主分类号： A61K31/538
- IPC分类号： A61K31/538
摘要：
The present invention provides formulations containing at least one unsaturated amphiphilic lipid and an amphipathic or hydrophobic drug and methods of making these formulations. In particular, the present invention provides formulations of at least one unsaturated phospholipid and an amphipathic or hydrophobic pyrimidine drug, methods of making these formulations and the use of such formulations in a variety of contexts, including, for example, the treatment of proliferative disorders, such as tumors and cancers.
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