专利检索 ap:("Rigel Pharmaceuticals, Inc.") AND inv:"PARMAR, Manjeet M." 第 1 页

1.

发明公开
FORMULATION OF INSOLUBLE SMALL MOLECULE THERAPEUTICS IN LIPID-BASED CARRIERS 审中-公开
标题翻译：配方介质中不溶，小分子剂对基于脂肪的

公开(公告)号：EP1959961A2

公开(公告)日：2008-08-27

申请号：EP06850222.8

申请日：2006-12-01

申请人： Rigel Pharmaceuticals, Inc.

发明人： PARMAR, Manjeet M.

IPC分类号： A61K31/538

CPC分类号： A61K31/538 , A61K9/127 , A61K31/70

摘要： The present invention provides formulations containing at least one unsaturated amphiphilic lipid and an amphipathic or hydrophobic drug and methods of making these formulations. In particular, the present invention provides formulations of at least one unsaturated phospholipid and an amphipathic or hydrophobic pyrimidine drug, methods of making these formulations and the use of such formulations in a variety of contexts, including, for example, the treatment of proliferative disorders, such as tumors and cancers.