发明公开
EP1962601A2 FUSED AMINOPIPERIDINES AS DIPEPTIDYL PEPTIDASE-4 INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES
有权
合并后的氨基哌啶，ALS二肽基肽酶-4抑制剂对于糖尿病的治疗或预防
- 专利标题： FUSED AMINOPIPERIDINES AS DIPEPTIDYL PEPTIDASE-4 INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES
- 专利标题（中）： 合并后的氨基哌啶，ALS二肽基肽酶-4抑制剂对于糖尿病的治疗或预防
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申请号： EP06845127.7申请日： 2006-12-08
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公开(公告)号： EP1962601A2公开(公告)日： 2008-09-03
- 发明人: COX, Jason, M. , EDMONDSON, Scott, D. , MASTRACCHIO, Anthony
- 申请人： Merck & Co., Inc.
- 申请人地址： 126 East Lincoln Avenue Rahway, NJ 07065-0907 US
- 专利权人： Merck & Co., Inc.
- 当前专利权人： Merck & Co., Inc.
- 当前专利权人地址： 126 East Lincoln Avenue Rahway, NJ 07065-0907 US
- 代理机构： Buchan, Gavin MacNicol
- 优先权： US750135P 20051214
- 国际公布： WO2007070434 20070621
- 主分类号： A01N43/40
- IPC分类号： A01N43/40 ; A61K31/45
摘要：
The present invention is directed to novel substituted fused aminopiperidines of structural formula (I) which are inhibitors of the dipeptidyl peptidase-4 enzyme and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-4 enzyme is involved, such as diabetes and particularly Type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-4 enzyme is involved.
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