发明公开
- 专利标题： NOVEL IMAGING AGENTS FOR FIBROSIS
- 专利标题（中）： 新的成像剂AGAINST囊性纤维化
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申请号： EP06831371.7申请日： 2006-12-07
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公开(公告)号： EP1962911A2公开(公告)日： 2008-09-03
- 发明人: TOLLESHAUG, Helge , NEWTON, Ben , RYDBECK, Anna , CHETTIBI, Salah , ERIKSEN, Morten
- 申请人： GE Healthcare Limited
- 申请人地址： Amersham Place Little Chalfont Buckinghamshire HP7 9NA GB
- 专利权人： GE Healthcare Limited
- 当前专利权人： GE Healthcare Limited
- 当前专利权人地址： Amersham Place Little Chalfont Buckinghamshire HP7 9NA GB
- 代理机构： Canning, Lewis R.
- 优先权： GB0524991 20051208
- 国际公布： WO2007066119 20070614
- 主分类号： A61K49/00
- IPC分类号： A61K49/00 ; A61K49/10 ; A61K49/14 ; A61K51/04 ; A61K103/10 ; A61K101/02
摘要：
The present invention provides a novel imaging agent suitable for the non-invasive visualization of fibrosis. A method for the preparation of the imaging agent is also provided by the invention, as well as a precursor for use in said method. Also provided is a pharmaceutical composition comprising the imaging agent and a kit for the preparation of the pharmaceutical. In a further aspect, use of the imaging agent for in vivo imaging and in the preparation of a medicament for the diagnosis of a condition in which LOX is upregulated is provided.
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