发明公开
- 专利标题： RADICICOL DERIVATIVES USEFUL FOR POSITRON EMISSION TOMOGRAPHY
- 专利标题（中）： 根赤壳衍生于成像正电子排放的
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申请号： EP07702563.3申请日： 2007-01-02
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公开(公告)号： EP1968964A1公开(公告)日： 2008-09-17
- 发明人: AUBERSON, Yves , BERGSTROEM, Mats , BRIARD, Emmanuelle , CHENE, Patrick , MARTARELLO, Laurent , SCHOEPFER, Joseph
- 申请人： Novartis AG
- 申请人地址： Lichtstrasse 35 4056 Basel CH
- 专利权人： Novartis AG
- 当前专利权人： Novartis AG
- 当前专利权人地址： Lichtstrasse 35 4056 Basel CH
- 代理机构： Vögeli-Lange, Regina
- 优先权： GB0526615 20051230
- 国际公布： WO2007077209 20070712
- 主分类号： C07D313/00
- IPC分类号： C07D313/00 ; C07D493/04 ; A61K51/04 ; G01N33/60
摘要：
The present invention relates to novel radicicol derivatives of the formula (I), in which R is R', (CH3)nCOOR' or (CH2)nCONHR, wherein R' is 11CH3, [3H]3C, [3H]2HC, [3H]H2C or (CH2)nHal, wherein Hal is 123I, 125I, 131I, I, 75Br, 76Br, 77Br, 82Br, Br, 18F or F, or R' is (CH2)n-1[3H]HCHal or (CH2)n-1[3H]2CHaI, wherein Hal is I, Br or F, and n is, each independently, 1 , 2, 3 or 4, in free form or in salt form, to their preparation, to their use as radiotracers/markers and to compositions containing them.
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