发明授权
- 专利标题： CYCLOALKYLAMINES AS MONOAMINE REUPTAKE INHIBITORS
- 专利标题（中）： 环烷基胺类称为单胺再摄取抑制剂
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申请号： EP07716419.2申请日： 2007-01-05
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公开(公告)号： EP1976513B1公开(公告)日： 2016-08-24
- 发明人: SHAO, Liming , WANG, Fengjiang , MALCOLM, Scott, Christopher , HEWITT, Michael, Charles , BUSH, Larry, R. , MA, Jianguo , VARNEY, Mark, A. , CAMPBELL, Una , ENGEL, Sharon, Rae , HARDY, Larry, Wendell , KOCH, Patrick , CAMPBELL, John, E.
- 申请人： Sunovion Pharmaceuticals Inc.
- 申请人地址： 84 Waterford Drive Marlborough, MA 01752-7010 US
- 专利权人： Sunovion Pharmaceuticals Inc.
- 当前专利权人： Sunovion Pharmaceuticals Inc.
- 当前专利权人地址： 84 Waterford Drive Marlborough, MA 01752-7010 US
- 代理机构： Camenisch, Andrew Richard
- 优先权： US756550P 20060106
- 国际公布： WO2007081857 20070719
- 主分类号： A61K31/381
- IPC分类号： A61K31/381 ; A61K31/335
摘要：
The invention relates to novel cyclohexylamine derivatives and their use in the treatment and/or prevention of central nervous system (CNS) disorders, such as depression, anxiety, schizophrenia and sleep disorder as well as methods for their synthesis. The invention also relates to pharmaceutical compositions containing the compounds of the invention, as well as methods of inhibiting reuptake of endogenous monoamines, such as dopamine, serotonin and norepinephrine from the synaptic cleft and methods of modulating one or more monoamine transporter.
公开/授权文献
- EP1976513A2 CYCLOALKYLAMINES AS MONOAMINE REUPTAKE INHIBITORS 公开/授权日：2008-10-08
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