发明公开
- 专利标题: THIAZOLES AS 11 BETA-HSD1 INHIBITORS
- 专利标题(中): 噻唑AS 11-β-HSD1抑制剂
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申请号: EP07703692.9申请日: 2007-01-08
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公开(公告)号: EP1979335A2公开(公告)日: 2008-10-15
- 发明人: GILLESPIE, Paul , GOODNOW JR., Robert Alan , KOWALCZYK, Agnieszka , LE, Kang , ZHANG, Qiang
- 申请人: F.HOFFMANN-LA ROCHE AG
- 申请人地址: Grenzacherstrasse 124 4070 Basel CH
- 专利权人: F.HOFFMANN-LA ROCHE AG
- 当前专利权人: F.HOFFMANN-LA ROCHE AG
- 当前专利权人地址: Grenzacherstrasse 124 4070 Basel CH
- 代理机构: Waschbüsch, Klaus
- 优先权: US759676P 20060118
- 国际公布: WO2007082808 20070726
- 主分类号: C07D277/56
- IPC分类号: C07D277/56 ; C07D417/06 ; C07D417/14 ; A61K31/427 ; A61P3/00 ; A61P37/00
摘要:
Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, type II diabetes mellitus and metabolic syndrome.
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