发明公开
- 专利标题: TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY
- 专利标题(中): 治疗杜兴肌营养不良症
-
申请号: EP07705369.2申请日: 2007-02-09
-
公开(公告)号: EP1986643A1公开(公告)日: 2008-11-05
- 发明人: WYNNE, Graham Michael , WREN, Stephen Paul , JOHNSON, Peter David , PRICE, Paul Damien , DE MOOR, Olivier , NUGENT, Gary , DORGAN, Colin Richard , STORER, Richard , PYE, Richard
- 申请人: Summit Corporation Plc
- 申请人地址: 91 Milton Park Abingdon Oxfordshire OX14 4RY GB
- 专利权人: Summit Corporation Plc
- 当前专利权人: Summit Corporation Plc
- 当前专利权人地址: 91 Milton Park Abingdon Oxfordshire OX14 4RY GB
- 代理机构: Ritter, Thomas Kurt
- 优先权: GB0602767 20060210; GB0617737 20060908; GB0623984 20061130
- 国际公布: WO2007091107 20070816
- 主分类号: A61K31/416
- IPC分类号: A61K31/416 ; A61K31/4192 ; A61P21/00
摘要:
There are disclosed compound of Formula (I) or (II) wherein A1, A2, A3, A4and A5, which may be the same or different, represent N or CR1, R9 represents - L -R3, in which L is a single bond or a linker group and R3 represents hydrogen or a substituent and in addition, when an adjacent pair of A1 - A4 each represent CR1, then the adjacent carbon atoms, together with their substituents may form a ring B, when A5 represents CR1, then A5 and N - R9, together with their substituents may form a ring C, or a harmaceutically acceptable salt thereof, in the manufacture of a medicament for the therapeutic and/or prophylactic treatment of Duchenne muscular dystrophy, Becker muscular dystrophy or cachexia.
信息查询
IPC分类: