发明公开
- 专利标题： Antisense inhibition of PTP1B expression
- 专利标题（中）： PTP1B表达的反义抑制
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申请号： EP08008871.9申请日： 2001-01-04
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公开(公告)号： EP2003207A3公开(公告)日： 2009-03-18
- 发明人: Cowsert, Lex, M. , Wyatt, Jacqueline, R.
- 申请人： Isis Pharmaceuticals, Inc.
- 申请人地址： 1896 Rutherford Road Carlsbad, CA 92008 US
- 专利权人： Isis Pharmaceuticals, Inc.
- 当前专利权人： Isis Pharmaceuticals, Inc.
- 当前专利权人地址： 1896 Rutherford Road Carlsbad, CA 92008 US
- 代理机构： Hallybone, Huw George
- 优先权： US487368 20000118
- 主分类号： C12N15/88
- IPC分类号： C12N15/88 ; C12N15/11 ; C12Q1/68 ; C07H21/04 ; A61K31/713
摘要：
Antisense compounds, compositions and methods are provided for modulating the expression of PTP1B. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding PTP1B. Methods of using these compounds for modulation of PTP1B expression and for treatment of diseases associated with expression of PTP1B are provided.
公开/授权文献
- EP2003207A2 Antisense inhibition of PTP1B expression 公开/授权日：2008-12-17
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