发明公开
- 专利标题： CYTOKINE-EXPRESSING CANCER IMMUNOTHERAPY COMBINATIONS
- 专利标题（中）： 细胞因子免疫治疗结合对抗癌症
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申请号： EP07754417.9申请日： 2007-03-28
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公开(公告)号： EP2007896A2公开(公告)日： 2008-12-31
- 发明人: LI, Betty , DU, Thomas , JOOSS, Karin
- 申请人： Cell Genesys Inc.
- 申请人地址： 500 Forbes Boulevard South San Francisco, CA 94080 US
- 专利权人： Cell Genesys Inc.
- 当前专利权人： Cell Genesys Inc.
- 当前专利权人地址： 500 Forbes Boulevard South San Francisco, CA 94080 US
- 代理机构： Roques, Sarah Elizabeth
- 优先权： US788216P 20060331; US728660 20070327
- 国际公布： WO2007123672 20071101
- 主分类号： C12P1/00
- IPC分类号： C12P1/00
摘要：
The present invention in all of its associated aspects provides improved methods and compositions for treating cancer in a mammal based on the sequential administration of the combination of a cytokine-expressing cancer immunotherapy composition and at least one tyrosine kinase inhibitor, wherein administration of the combination results in enhanced therapeutic efficacy relative to administration of the cytokine-expressing cancer immunotherapy composition or at least one tyrosine kinase inhibitor as a monotherapy.
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