发明公开
EP2010680A2 METHODS AND MEANS FOR ASSESSING HIV GAG/PROTEASE INHIBITOR THERAPY
审中-公开
的方法和手段进行评估HIV GAG /蛋白酶抑制剂治疗
- 专利标题： METHODS AND MEANS FOR ASSESSING HIV GAG/PROTEASE INHIBITOR THERAPY
- 专利标题（中）： 的方法和手段进行评估HIV GAG /蛋白酶抑制剂治疗
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申请号： EP07765259.2申请日： 2007-04-13
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公开(公告)号： EP2010680A2公开(公告)日： 2009-01-07
- 发明人: DE BAERE, Inky Paul Madeleine , KRAUS, Guenter , RIMSKY, Laurence Tatiana , MAES, Bart Anna Julien , AZIJN, Hilde , DE BETHUNE, Marie-Pierre T.M.M.G
- 申请人： Tibotec Pharmaceuticals Ltd.
- 申请人地址： Eastgate Village Little Island, Co. Cork IE
- 专利权人： Tibotec Pharmaceuticals Ltd.
- 当前专利权人： Tibotec Pharmaceuticals Ltd.
- 当前专利权人地址： Eastgate Village Little Island, Co. Cork IE
- 代理机构： Daelemans, Frank F.R.
- 优先权： EP06112680 20060414
- 国际公布： WO2007118849 20071025
- 主分类号： C12Q1/70
- IPC分类号： C12Q1/70 ; C12Q1/68 ; G01N33/68 ; C12N15/09
摘要：
The present invention relates to methods and means for the evaluation of HIV treatment. In particular, molecular events at the HIV gag and protease proteins and their effect on therapeutic efficacy of drugs are determined. The methods rely on providing HIV gag and protease nucleic acid material and evaluating a treatment either through genotyping or phenotyping. Said method may find use in multiple fields including diagnostics, drug screening, pharmacogenetics and drug development.
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