发明公开
EP2011883A1 METHOD OF PREDICTING SKIN SPOT FORMATION AND METHOD OF SCREENING SKIN SPOT FORMATION INHIBITOR WITH THE USE OF SPOT SITE-INCREASING GENES AS INDICATION
审中-公开
一种用于预测皮肤丘疹的筛选抑制剂皮肤疙瘩教育的形成和模式使用指向疙瘩放大基因，指标
- 专利标题： METHOD OF PREDICTING SKIN SPOT FORMATION AND METHOD OF SCREENING SKIN SPOT FORMATION INHIBITOR WITH THE USE OF SPOT SITE-INCREASING GENES AS INDICATION
- 专利标题（中）： 一种用于预测皮肤丘疹的筛选抑制剂皮肤疙瘩教育的形成和模式使用指向疙瘩放大基因，指标
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申请号： EP07742776.3申请日： 2007-04-24
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公开(公告)号： EP2011883A1公开(公告)日： 2009-01-07
- 发明人: AOKI, Hirofumi , KISHIMOTO, Jiro , MORO, Osamu
- 申请人： Shiseido Company, Limited
- 申请人地址： 5-5, Ginza 7-chome Chuo-ku Tokyo 104-8010 JP
- 专利权人： Shiseido Company, Limited
- 当前专利权人： Shiseido Company, Limited
- 当前专利权人地址： 5-5, Ginza 7-chome Chuo-ku Tokyo 104-8010 JP
- 代理机构： Ulmann, Catherine Claire
- 优先权： JP2006120479 20060425
- 国际公布： WO2007126104 20071108
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; A61K45/00 ; A61P17/16 ; C12N15/09 ; G01N33/15 ; G01N33/50
摘要：
The present invention provides a skin test method for predicting the formation of spots in the skin. This method is characterized by judging skin to be susceptible to spot formation in the case expression of genes consisting of MLSTD1, MOGAT1, FADS2, FADS1, HSD3B1, ELOVL3, BG1, PECR, FABP7, FA2H, HAO2, ALOX15B, PDE6A, LZTS1, SEC14L4, BAMBI, CIDEA, TERE1, GAL, THRSP, INSIG1 or CUTL2 in the epidermis is accelerated, or the expression of genes consisting of RBBP6, MSMB, WIF1, ANKRD12, FLG, SYNE2, SCEL, NKTR or AMBP in the epidermis is decreased as compared with normal expression in the epidermis.
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