发明公开
- 专利标题： METHOD FOR SYNTHESIZING THYMOSINS
- 专利标题（中）： VERFAHREN ZUR SYNTHETISIERUNG VON THYMOSINEN
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申请号： EP07765833.4申请日： 2007-04-25
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公开(公告)号： EP2019118A1公开(公告)日： 2009-01-28
- 发明人: FERNANDEZ CARNEADO, Jimena , PONSATI OBIOLS, Berta , CLEMENTE RODRIGUEZ, Javier , RUBIRES FERRER, Raimon , PAVON FERNANDEZ, Sergi
- 申请人： BCN Peptides, S.A.
- 申请人地址： Polígono Industrial Els Vinyets-Els Fogars, 2, Carretera C-244 Km 22 Sant Quinti de Mediona Barcelona ES
- 专利权人： BCN Peptides, S.A.
- 当前专利权人： BCN Peptides, S.A.
- 当前专利权人地址： Polígono Industrial Els Vinyets-Els Fogars, 2, Carretera C-244 Km 22 Sant Quinti de Mediona Barcelona ES
- 代理机构： Carvajal y Urquijo, Isabel
- 优先权： ES200601197 20060510
- 国际公布： WO2007132037 20071122
- 主分类号： C07K14/575
- IPC分类号： C07K14/575 ; C07K17/08 ; A61K38/22 ; A61P29/00 ; A61P35/00
摘要：
The invention relates to a method for obtaining thymosins and/or the pharmaceutically acceptable salts thereof by means of solid-phase synthesis on polymeric supports, which comprises the steps of linearly synthesizing the thymus-derived peptides in solid phase, incorporating at least one Thr or Ser in the sequence, in pseudoproline dipeptide form, obtaining the thymosins by treating the peptidyl resin with trifluoroacetic acid, and purifying the thymosins by RP-HPLC. The present invention also protects the isolated and/or purified compound obtained by means of said method and also the use thereof in the preparation of a medicinal product.
公开/授权文献
- EP2019118B1 METHOD FOR SYNTHESIZING THYMOSINS 公开/授权日：2012-11-07
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