Methods and apparatus are described for DWDM transport of CATV and digital signals over optical fiber in low-dispersion spectral regions. A method includes transporting a plurality of optical carriers of different wavelengths over an optical link using wavelength division multiplexing, the optical link including a plurality of optical segments. The plurality of optical channel center wavelengths defined by the plurality of optical carriers are clustered proximate an average value of a zero-dispersion wavelength of the optical link, or near either a) a low wavelength edge or b) a high wavelength edge of a range of zero-dispersion wavelengths of the optical link and a plurality of optical channel center frequencies defined by the plurality of optical channel center wavelengths are non-uniformly spaced apart.