发明公开
EP2035092A2 USE OF KW-3902 FOR ACHIEVING DIURESIS IN PATIENTS WITH CONGESTIVE HEART FAILURE AND ACUTE FLUID OVERLOAD
审中-公开
KW-3902的使用能达到排尿在与心脏衰竭和急性积液患者充血
- 专利标题： USE OF KW-3902 FOR ACHIEVING DIURESIS IN PATIENTS WITH CONGESTIVE HEART FAILURE AND ACUTE FLUID OVERLOAD
- 专利标题（中）： KW-3902的使用能达到排尿在与心脏衰竭和急性积液患者充血
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申请号： EP07796072.2申请日： 2007-06-12
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公开(公告)号： EP2035092A2公开(公告)日： 2009-03-18
- 发明人: DITTRICH, Howard , FARMER, Brian , WOODS, Randy
- 申请人： Novacardia, Inc.
- 申请人地址： 12651 High Bluff Drive Suite 200 San Diego, CA 92130 US
- 专利权人： Novacardia, Inc.
- 当前专利权人： Novacardia, Inc.
- 当前专利权人地址： 12651 High Bluff Drive Suite 200 San Diego, CA 92130 US
- 代理机构： Hussain, Deeba
- 优先权： US814109P 20060616
- 国际公布： WO2007149283 20071227
- 主分类号： A61P7/10
- IPC分类号： A61P7/10 ; A61K31/4985 ; A61K31/635 ; A61K45/06
摘要：
Methods of treating patients with acute fluid overload comprising administering diuretic therapy and an amount of KW-3902, a pharmaceutically acceptable salt, ester, amide, metabolite, or prodrug thereof, effective to accelerate removal of excess fluid from the patient in comparison to diuretic therapy alone. Methods of improving the treatment time to achieve adequate diuresis in an individual experiencing acute fluid overload comprising administering to said individual a diuretic and a therapeutically effective amount of KW-3902 or a pharmaceutically acceptable salt, ester, amide, metabolite, or prodrug thereof.
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