发明公开
- 专利标题: N-TERMINAL DERIVATISATION OF PROTEINS WITH POLYSACCHARIDES
- 专利标题(中): 离合器多聚AM N末端蛋白的
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申请号: EP07766361.5申请日: 2007-07-25
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公开(公告)号: EP2043616A1公开(公告)日: 2009-04-08
- 发明人: JAIN, Sanjay , LAING, Peter , GREGORIADIS, Gregory
- 申请人: Lipoxen Technologies Limited
- 申请人地址: London BioScience Innovation Centre 2 Royal College Street London NW1 0NH GB
- 专利权人: Lipoxen Technologies Limited
- 当前专利权人: Lipoxen Technologies Limited
- 当前专利权人地址: London BioScience Innovation Centre 2 Royal College Street London NW1 0NH GB
- 代理机构: Jones, Helen M.M.
- 优先权: EP06117830 20060725
- 国际公布: WO2008012540 20080131
- 主分类号: A61K9/22
- IPC分类号: A61K9/22 ; A61K31/198 ; A61K9/20 ; A61K31/195
摘要:
A composition comprises a population of polysaccharide derivatives of a protein, wherein the protein is insulin or an insulin-like protein and the polysaccharide is anionic and comprises between 2 and 125 saccharide units, and wherein the population consists substantially only of derivatives of the protein derivatised at the N-terminal of the B-chain.
公开/授权文献
- EP2043616B1 N-TERMINAL CONJUGATION OF POLYSIALIC ACID TO PROTEINS 公开/授权日:2016-01-27
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