发明公开
- 专利标题： SUPPRESSOR TRNA TRANSCRIPTION IN VERTEBRATE CELLS
- 专利标题（中）： 抑制剂TRNA在脊椎细胞中的转录
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申请号： EP07837972.4申请日： 2007-09-07
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公开(公告)号： EP2064333A2公开(公告)日： 2009-06-03
- 发明人: TIAN, Feng , NORMAN, Thea , CHU, Stephanie
- 申请人： Ambrx, Inc.
- 申请人地址： 10975 North Torrey Pines Road, Suite 100 La Jolla CA 92037 US
- 专利权人： Ambrx, Inc.
- 当前专利权人： Ambrx, Inc.
- 当前专利权人地址： 10975 North Torrey Pines Road, Suite 100 La Jolla CA 92037 US
- 代理机构： Mercer, Christopher Paul
- 优先权： US843264P 20060908
- 国际公布： WO2008030614 20080313
- 主分类号： C12P21/06
- IPC分类号： C12P21/06 ; C12N1/21
摘要：
This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in vertebrate cells. The components include orthogonal tRNA's, orthogonal aminoacyl-tRNA synthetases, orthogonal pairs of tRNA's/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in vertebrate cells are also provided.
公开/授权文献
- EP2064333B1 SUPPRESSOR TRNA TRANSCRIPTION IN VERTEBRATE CELLS 公开/授权日：2014-02-26
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