发明授权
EP2074096B1 3-PYRIDINECARBOXAMIDE AND 2-PYRAZINECARBOXAMIDE DERIVATIVES AS HDL-CHOLESTEROL RAISING AGENTS
有权
作为HDL-胆固醇升高剂的3-吡啶酰胺酰胺和2-吡嗪酰胺酰胺衍生物
- 专利标题: 3-PYRIDINECARBOXAMIDE AND 2-PYRAZINECARBOXAMIDE DERIVATIVES AS HDL-CHOLESTEROL RAISING AGENTS
- 专利标题(中): 作为HDL-胆固醇升高剂的3-吡啶酰胺酰胺和2-吡嗪酰胺酰胺衍生物
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申请号: EP07820501.0申请日: 2007-09-24
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公开(公告)号: EP2074096B1公开(公告)日: 2012-06-27
- 发明人: ANDJELKOVIC, Mirjana , BÉNARDEAU, Agnès , CHAPUT, Evelyne , HEBEISEN, Paul , NETTEKOVEN, Matthias , OBST SANDER, Ulrike , PANOUSIS, Constantinos G. , ROEVER, Stephan
- 申请人: F.Hoffmann-La Roche AG
- 申请人地址: Grenzacherstrasse 124 4070 Basel CH
- 专利权人: F.Hoffmann-La Roche AG
- 当前专利权人: F.Hoffmann-La Roche AG
- 当前专利权人地址: Grenzacherstrasse 124 4070 Basel CH
- 代理机构: Klostermeyer-Rauber, Dörte
- 优先权: EP06121755 20061004
- 国际公布: WO2008040651 20080410
- 主分类号: C07D213/63
- IPC分类号: C07D213/63 ; C07D213/74 ; C07D241/24 ; A61K31/465 ; A61K31/4965 ; A61P9/00
摘要:
The present invention relates to the use of compounds of the formula wherein A, G, R1 to R8 and R17 are as defined in the description, for the preparation of medicaments for the treatment and/or prophylaxis of diseases which can be treated with HDL-cholesterol raising agents, such as peripheral vascular disease, dyslipidemia, hyperbetalipoproteinemia, hypoalphalipoproteinemia, hypercholesterolemia, hypertriglyceridemia, familial hypercholesterolemia, cardiovascular disorders, angina, ischemia, cardiac ischemia, stroke, myocardial infarction, reperfusion injury, angioplastic restenosis, hypertension, and vascular complications of diabetes, obesity or endotoxemia.
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