发明公开
- 专利标题： METHODS OF TREATING DISORDERS ASSOCIATED WITH FAT STORAGE
- 专利标题（中）： 法疾病治疗的脂肪储存相关的
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申请号： EP07825768.0申请日： 2007-09-24
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公开(公告)号： EP2086574A2公开(公告)日： 2009-08-12
- 发明人: SANCHEZ-GARCIA, Isidro , PEREZ-MANCERA, Pedro A
- 申请人： Universidad De Salamanca , CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
- 申请人地址： Patio de Escuelas 1 37008 Salamanca ES
- 专利权人： Universidad De Salamanca,CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
- 当前专利权人： Universidad De Salamanca,CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
- 当前专利权人地址： Patio de Escuelas 1 37008 Salamanca ES
- 代理机构： Goodfellow, Hugh Robin
- 优先权： EP06076886 20061016
- 国际公布： WO2008047235 20080424
- 主分类号： A61K39/00
- IPC分类号： A61K39/00
摘要：
The invention relates, in general, to markers of obesity and lipodystrophy. In particular, the expression level of the SLUG gene or its expression products can be used as such a marker. Furthermore, the invention additionally relates to the use of SLUG as a therapeutic and diagnostic target for these pathologies. The invention further relates to a method of treating a disorder associated with increased or decreased fat storage in a mammal comprising modulating the activity or level of the SLUG protein or the SLUG gene in the mammal.
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