发明授权
- 专利标题： SPIRO-PIPERIDINE DERIVATIVES
- 专利标题（中）： 螺哌啶衍生物
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申请号： EP07847384.0申请日： 2007-11-27
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公开(公告)号： EP2099799B1公开(公告)日： 2010-06-02
- 发明人: BISSANTZ, Caterina , GRUNDSCHOBER, Christophe , MASCIADRI, Raffaello , RATNI, Hasane , ROGERS-EVANS, Mark , SCHNIDER, Patrick
- 申请人： F.HOFFMANN-LA ROCHE AG
- 申请人地址： Grenzacherstrasse 124 4070 Basel CH
- 专利权人： F.HOFFMANN-LA ROCHE AG
- 当前专利权人： F.HOFFMANN-LA ROCHE AG
- 当前专利权人地址： Grenzacherstrasse 124 4070 Basel CH
- 代理机构： Salud, Carlos E.
- 优先权： EP06125645 20061207
- 国际公布： WO2008068159 20080612
- 主分类号： C07D471/10
- IPC分类号： C07D471/10 ; C07D498/10 ; A61K31/438 ; A61P9/02
摘要：
Present invention is concerned with novel indol-2-yl-carbonyl-spiro-piperidine derivatives as V1a receptor antagonists, their manufacture, pharmaceutical compositions containing them and their use as medicaments. The active compounds of the present invention are useful in the prevention and/or treatment of anxiety and depressive disorders and other diseases. The compounds of present invention have the general Formula (I) wherein R1 to R11 and X are as defined in the description.
公开/授权文献
- EP2099799A1 SPIRO-PIPERIDINE DERIVATIVES 公开/授权日：2009-09-16
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