发明公开
- 专利标题: RHO KINASE INHIBITORS
- 专利标题(中): RHO激酶抑制剂
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申请号: EP08727346.2申请日: 2008-01-02
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公开(公告)号: EP2114869A1公开(公告)日: 2009-11-11
- 发明人: DAHMANN, Georg , HICKEY, Eugene, Richard , LI, Xiang , MAO, Wang , MARSHALL, Daniel, Richard , MORWICK, Tina, Marie , SIBLEY, Robert , SNOW, Roger, John , SORCEK, Ronald, John , WU, Frank , YOUNG, Erick, Richard, Roush
- 申请人: Boehringer Ingelheim International GmbH , Boehringer Ingelheim Pharma GmbH & Co. KG
- 申请人地址: Binger Strasse 173 55216 Ingelheim DE
- 专利权人: Boehringer Ingelheim International GmbH,Boehringer Ingelheim Pharma GmbH & Co. KG
- 当前专利权人: Boehringer Ingelheim International GmbH,Boehringer Ingelheim Pharma GmbH & Co. KG
- 当前专利权人地址: Binger Strasse 173 55216 Ingelheim DE
- 代理机构: Hammann, Heinz
- 优先权: US878625P 20070103
- 国际公布: WO2008086047 20080717
- 主分类号: C07C237/42
- IPC分类号: C07C237/42 ; C07C275/42 ; C07D217/22 ; A61K31/167 ; A61K31/277 ; A61K31/472 ; A61P9/10
摘要:
Substituted amide and urea derivatives useful as inhibitors of Rho kinase are described, which inhibitors can be useful in the treatment of various disorders such as cardiovascular diseases, cancer, neurological diseases, renal diseases, bronchial asthma, erectile dysfunction and glaucoma.
公开/授权文献
- EP2114869B1 RHO KINASE INHIBITORS 公开/授权日:2014-07-23
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