摘要:
The present application relates to compounds of any one of Formulae I, Ia, Ib, Ic, Id, Ie, and If. Compounds of Formula I have the structure:
wherein A, B, Y, Z, R 2 , R 4 , R 5 , R 6 , R q and q are as defined herein. The compounds can be used as inhibitors of Bcl-3 and can be used for the treatment of cancer, particularly metastatic cancer.
摘要:
A pest control agent containing a compound represented by the following Formula (1), wherein A represents a carbon atom, a nitrogen atom, or the like, K represents a non-metal atom group necessary for forming a cyclic linking group derived from a 5- or 6-membered aromatic ring, in combination with A and two carbon atoms to which A bonds, X represents a hydrogen atom, a halogen atom, or the like, n represents an integer of from 0 to 4, T represents -C(=G 1 )-Q 1 (wherein G 1 and G 2 represent an oxygen atom or the like, Q 1 represents a phenyl group which may have a substituent, a heterocyclic group which may have a substituent, or the like), or the like, Q 2 represents a phenyl group or the like, G 3 represents an oxygen atom or the like, and R 1 and R 2 each independently represent a hydrogen atom, a C1-C6 alkyl group, or a group represented by -L-D, or the like (provided that at least either R 1 or R 2 represents a group represented by -L-D); as an active ingredient exhibits an excellent effect.
摘要:
The invention provides an imide compound represented by the following Formula (1) and an insecticide including the imide compound: wherein, each of A 1 , A 2 , A 3 , and A 4 represents a carbon atom, a nitrogen atom, or an oxidized nitrogen atom; R 1 represents a hydrogen atom, an alkyl group which may be substituted, or a C2-C4 alkylcarbonyl group which may be substituted; each of G 1 and G 2 independently represents an oxygen atom or a sulfur atom; each X may be the same as or different from one another and represents a hydrogen atom, a halogen atom, a C1-C3 alkyl group, or a trifluoromethyl group; n represents an integer from 0 to 4; and each of Q 1 and Q 2 represents a phenyl group, naphthyl group, or a heterocyclic group, each of which may be substituted.
摘要翻译:本发明提供由下式(1)表示的酰亚胺化合物和包括酰亚胺化合物的杀虫剂:其中,A 1,A 2,A 3和A 4各自表示碳原子,氮原子或氧化的 氮原子 R 1表示氢原子,可被取代的烷基或可被取代的C2-C4烷基羰基; G 1和G 2各自独立地表示氧原子或硫原子; 每个X可以彼此相同或不同,表示氢原子,卤素原子,C1-C3烷基或三氟甲基; n表示0〜4的整数, Q 1和Q 2各自表示可以被取代的苯基,萘基或杂环基。
摘要:
The present invention is related to the preparation and pharmaceutical use of novel benzamide derivatives as defined in the specification of formula (I) as histone deacetylase inhibitors (HDACI), their preparations and the methods of using these compounds or their pharmaceutically acceptable salt in the treatment of cell proliferative diseases, e.g. cancer and psoriasis.