发明公开
EP2119703A1 NOVEL INDOLE DERIVATIVE HAVING INHIBITORY ACTIVITY ON I B KINASE
有权
消除了印度麻醉师HEMMENDER WIRKUNG AUF I-B-KINASE
- 专利标题: NOVEL INDOLE DERIVATIVE HAVING INHIBITORY ACTIVITY ON I B KINASE
- 专利标题(中): 消除了印度麻醉师HEMMENDER WIRKUNG AUF I-B-KINASE
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申请号: EP08703206.6申请日: 2008-01-15
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公开(公告)号: EP2119703A1公开(公告)日: 2009-11-18
- 发明人: ENOMOTO, Hiroshi , KAWASHIMA, Kenji , KUDOU, Kazuhiro , YAMAMOTO, Minoru , MURAI, Masaaki , INABA, Takaaki , ISHIZAKA, Noriko
- 申请人: Santen Pharmaceutical Co., Ltd
- 申请人地址: 9-19, Shimoshinjo 3-chome Higashiyodogawa-ku Osaka-shi Osaka 533-8651 JP
- 专利权人: Santen Pharmaceutical Co., Ltd
- 当前专利权人: Santen Pharmaceutical Co., Ltd
- 当前专利权人地址: 9-19, Shimoshinjo 3-chome Higashiyodogawa-ku Osaka-shi Osaka 533-8651 JP
- 代理机构: Müller-Boré & Partner Patentanwälte
- 优先权: JP2007005554 20070115
- 国际公布: WO2008087933 20080724
- 主分类号: C07D209/42
- IPC分类号: C07D209/42 ; A61K31/404 ; A61K31/4439 ; A61K31/47 ; A61P3/00 ; A61P3/10 ; A61P5/00 ; A61P9/00 ; A61P17/00 ; A61P25/00 ; A61P27/02 ; A61P27/06 ; A61P29/00 ; A61P31/00 ; A61P35/00 ; A61P37/06 ; A61P37/08 ; A61P43/00 ; C07D401/04 ; C07D403/04
摘要:
Disclosed is a compound represented by the general formula (1) or a salt thereof. The compound or a salt thereof has an inhibitory activity on IKKβ and is therefore useful as preventive and/or therapeutic agent for a disease associated with IKKβ. In the formula, R 1 represents a hydrogen atom, a lower alkyl group, an aryl group, a hydroxy group, or the like; R 2 represents a halogen atom, a lower alkyl group, a lower alkenyl group, a lower alkynyl group, or the like; and m represents 0, 1, 2, or the like.
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