发明公开
- 专利标题: NOVEL LYSYL OXIDASES
- 专利标题(中): 新的赖氨酰氧化酶
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申请号: EP08717945.3申请日: 2008-03-18
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公开(公告)号: EP2126060A1公开(公告)日: 2009-12-02
- 发明人: DIJK, VAN, Albertus, Alard , DEKKER, Petrus, Jacobus, Theodorus , WESTERLAKEN, Ilja , BAKHUIS, Janna Gardina
- 申请人: DSM IP Assets B.V.
- 申请人地址: Het Overloon 1 6411 TE Heerlen NL
- 专利权人: DSM IP Assets B.V.
- 当前专利权人: DSM IP Assets B.V.
- 当前专利权人地址: Het Overloon 1 6411 TE Heerlen NL
- 代理机构: Matulewicz, Emil Rudolf Antonius
- 优先权: EP07104645 20070322; EP07123028 20071212
- 国际公布: WO2008113799 20080925
- 主分类号: C12N9/06
- IPC分类号: C12N9/06 ; C12P21/06 ; A23L1/00 ; C12P21/00
摘要:
The present invention relates to an isolated lysyl oxidase which is able to catalyze the oxidative deamination of lysyl groups in proteins or peptides to the corresponding aldehydes, with the subsequent reduction of O2 to H2O2 whereby the lysyl oxidase (a) shows a ratio of between lysyl oxidase activity for Ac-Gly-Lys-OMe and lysyl oxidase activity for benzylamine of at least 1.1, preferably at least 1.3, more preferably of at least 1.4 whereby the activities are determined at 37 degrees Celsius and an pH of 7.0; and. (b) has an optimum activity at a temperature of between 0 and 60 degrees Celcius.
公开/授权文献
- EP2126060B1 NOVEL LYSYL OXIDASES 公开/授权日:2016-10-05
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