发明公开
EP2131839A2 COMPOSITIONS COMPRISING DERIVATIVES OF 3-PHENYLPYRIDAZINE FOR TREATING SEIZURE-RELATED DISORDERS
审中-公开
3-苯基哒嗪用于疾病发作与处理组合物衍生物
- 专利标题： COMPOSITIONS COMPRISING DERIVATIVES OF 3-PHENYLPYRIDAZINE FOR TREATING SEIZURE-RELATED DISORDERS
- 专利标题（中）： 3-苯基哒嗪用于疾病发作与处理组合物衍生物
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申请号： EP08731122.1申请日： 2008-02-29
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公开(公告)号： EP2131839A2公开(公告)日： 2009-12-16
- 发明人: WATTERSON, D. Martin , VAN ELDIK, Linda, J. , WAINWRIGHT, Mark, S.
- 申请人： Northwestern University
- 申请人地址： 633 Clark Street Evanston, IL 60608 US
- 专利权人： Northwestern University
- 当前专利权人： Northwestern University
- 当前专利权人地址： 633 Clark Street Evanston, IL 60608 US
- 代理机构： Holliday, Louise Caroline
- 优先权： US904606P 20070302; US4385P 20071127
- 国际公布： WO2008109437 20080912
- 主分类号： A61K31/4164
- IPC分类号： A61K31/4164 ; A61K31/426 ; A61K31/50 ; A61K31/501 ; A61K31/502 ; A61K31/506 ; A61K31/551 ; A61P25/08 ; A61P25/00
摘要：
The present invention relates to therapeutic and/or prophylactic uses of pyridazine compounds and to pharmaceutical compositions containing one or more of these compounds as an active component for treating a disorder characterized by conduction disturbances, electroconvulsions and/or seizures, in particular epilepsy, more particularly pediatric epilepsy. In an aspect of the invention, the pyridazine compound has the Formula (Ia) or (Ib) wherein R
1 , R
2 , R
3 , R
4 , R
5 , R
6 and R
7 are as defined in the description.
1 , R
2 , R
3 , R
4 , R
5 , R
6 and R
7 are as defined in the description.
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