公开(公告)号：EP2131839A2

公开(公告)日：2009-12-16

申请号：EP08731122.1

申请日：2008-02-29

申请人： Northwestern University

发明人： WATTERSON, D. Martin ,  VAN ELDIK, Linda, J. ,  WAINWRIGHT, Mark, S.

IPC分类号： A61K31/4164 ,  A61K31/426 ,  A61K31/50 ,  A61K31/501 ,  A61K31/502 ,  A61K31/506 ,  A61K31/551 ,  A61P25/08 ,  A61P25/00

CPC分类号： A61K31/506 ,  A61K31/4164 ,  A61K31/426 ,  A61K31/50 ,  A61K31/501 ,  A61K31/502 ,  A61K31/551

摘要： The present invention relates to therapeutic and/or prophylactic uses of pyridazine compounds and to pharmaceutical compositions containing one or more of these compounds as an active component for treating a disorder characterized by conduction disturbances, electroconvulsions and/or seizures, in particular epilepsy, more particularly pediatric epilepsy. In an aspect of the invention, the pyridazine compound has the Formula (Ia) or (Ib) wherein R
1 , R
2 , R
3 , R
4 , R
5 , R
6 and R
7 are as defined in the description.