发明公开
- 专利标题： TWO-STEP TEMPERATURE PROFILE FOR THE PROPAGATION OF VIRUSES
- 专利标题（中）： 两阶段的温度分布进行了病毒的传播
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申请号： EP08749279.9申请日： 2008-04-30
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公开(公告)号： EP2155863A1公开(公告)日： 2010-02-24
- 发明人: REITER, Manfred , GRILLBERGER, Leopold , MUNDT, Wolfgang
- 申请人： Baxter International Inc. , Baxter Healthcare S.A.
- 申请人地址： One Baxter Parkway Deerfield, IL 60015 US
- 专利权人： Baxter International Inc.,Baxter Healthcare S.A.
- 当前专利权人： Baxter International Inc.,Baxter Healthcare S.A.
- 当前专利权人地址： One Baxter Parkway Deerfield, IL 60015 US
- 代理机构： Müller-Boré & Partner Patentanwälte
- 优先权： US927693P 20070504
- 国际公布： WO2008135230 20081113
- 主分类号： C12N7/00
- IPC分类号： C12N7/00 ; C12N7/02
摘要：
The present invention provides a method for the production of a virus. The method includes providing a host cell that has been infected by the virus and cultivating the infected host cell at two different temperatures. The virus produced by the cultivation steps is subsequently collected. By using the dual temperature cultivation process, high titer and improved purity can be obtained.
公开/授权文献
- EP2155863B1 TWO-STEP TEMPERATURE PROFILE FOR THE PROPAGATION OF VIRUSES 公开/授权日：2014-08-13
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