发明公开
- 专利标题: FAMILY OF PFKFB3 INHIBITORS WITH ANTI-NEOPLASTIC ACTIVITIES
- 专利标题(中): 家庭,抗肿瘤药影响PFKFB3缓蚀剂
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申请号: EP08768587.1申请日: 2008-06-18
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公开(公告)号: EP2167058A2公开(公告)日: 2010-03-31
- 发明人: CHESNEY, Jason , TRENT, John, O. , TELANG, Sucheta , CLEM, Brian , MEIER, Jason
- 申请人: University Of Louisville Research Foundation, Inc.
- 申请人地址: Jouett Hall 2301 South Third Street Suite LL02 Louisville KY 40208 US
- 专利权人: University Of Louisville Research Foundation, Inc.
- 当前专利权人: University Of Louisville Research Foundation, Inc.
- 当前专利权人地址: Jouett Hall 2301 South Third Street Suite LL02 Louisville KY 40208 US
- 代理机构: Sandmann, Wolfgang
- 优先权: US936030P 20070618
- 国际公布: WO2008156783 20081224
- 主分类号: A61K31/00
- IPC分类号: A61K31/00 ; A61K31/12 ; A61K31/121 ; A61P33/00
摘要:
A methods and compounds for inhibiting 6-phosphofructo-2- kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) are described. Also described are methods of inhibiting cell proliferation, treating cancer, and screening compounds to determine their ability to inhibit PFKFB3.
公开/授权文献
- EP2167058B1 FAMILY OF PFKFB3 INHIBITORS WITH ANTI-NEOPLASTIC ACTIVITIES 公开/授权日:2015-08-12
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