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公开(公告)号:EP2167058B1
公开(公告)日:2015-08-12
申请号:EP08768587.1
申请日:2008-06-18
发明人: CHESNEY, Jason , TRENT, John, O. , TELANG, Sucheta , CLEM, Brian , MEIER, Jason
IPC分类号: A61K31/00 , A61K31/12 , A61K31/121 , A61P33/00
CPC分类号: A61K31/121 , A61K31/00 , A61K31/12
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公开(公告)号:EP2167058A2
公开(公告)日:2010-03-31
申请号:EP08768587.1
申请日:2008-06-18
发明人: CHESNEY, Jason , TRENT, John, O. , TELANG, Sucheta , CLEM, Brian , MEIER, Jason
IPC分类号: A61K31/00 , A61K31/12 , A61K31/121 , A61P33/00
CPC分类号: A61K31/121 , A61K31/00 , A61K31/12
摘要: A methods and compounds for inhibiting 6-phosphofructo-2- kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) are described. Also described are methods of inhibiting cell proliferation, treating cancer, and screening compounds to determine their ability to inhibit PFKFB3.
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