发明公开
- 专利标题： BICYCLIC SPHINGOSINE 1-PHOSPHATE ANALOGS
- 专利标题（中）： BICYCLISCHE SPHINGOSIN-1-PHOSPHATANALOGA
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申请号： EP08798022.3申请日： 2008-08-15
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公开(公告)号： EP2190852A1公开(公告)日： 2010-06-02
- 发明人: LYNCH, Kevin, R. , MACDONALD, Timothy, L. , GUCKIAN, Kevin , LIN, Edward, Yin-shiang ,
- 申请人： University Of Virginia Patent Foundation , Biogen Idec MA Inc.
- 申请人地址： 250 West Main Street Suite 300 Charlottesville, VA 22902 US
- 专利权人： University Of Virginia Patent Foundation,Biogen Idec MA Inc.
- 当前专利权人： University Of Virginia Patent Foundation,Biogen Idec MA Inc.
- 当前专利权人地址： 250 West Main Street Suite 300 Charlottesville, VA 22902 US
- 代理机构： Lucas, Brian Ronald
- 优先权： US956111P 20070815
- 国际公布： WO2009023854 20090219
- 主分类号： C07F9/09
- IPC分类号： C07F9/09 ; C07C215/08 ; C07C215/10 ; C07D271/06 ; C07D333/16 ; C07D413/04 ; A61K31/133 ; A61K31/381 ; A61K31/4245 ; A61K31/661 ; A61P19/00
摘要：
Compounds that have agonist activity at one or more of the SlP receptors are provided. The compounds are sphingosine analogs that, after phosphorylation, can behave as agonists at SlP receptors. Formula (I):
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