发明公开
- 专利标题： N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF
- 专利标题（中）： N-苯基苯并噻吩酸衍生物及其用途
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申请号： EP08808058.5申请日： 2008-09-18
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公开(公告)号： EP2203411A2公开(公告)日： 2010-07-07
- 发明人: ATTALI, Bernard , PERETZ, Asher
- 申请人： Ramot at Tel-Aviv University Ltd.
- 申请人地址： P.O. Box 39296 61392 Tel Aviv IL
- 专利权人： Ramot at Tel-Aviv University Ltd.
- 当前专利权人： Ramot at Tel-Aviv University Ltd.
- 当前专利权人地址： P.O. Box 39296 61392 Tel Aviv IL
- 代理机构： Fichter, Robert Arno
- 优先权： US960215P 20070920; US996398P 20071115
- 国际公布： WO2009037707 20090326
- 主分类号： C07C229/42
- IPC分类号： C07C229/42 ; C07C229/38 ; C07C237/34 ; C07C219/32 ; A61P9/10 ; A61P25/16 ; A61P25/28 ; A61K31/136
摘要：
ABSTRACT Compounds that can be used as openers or blockers of voltage-dependent potassium channels, and which are useful in the treatment of conditions such as central or peripheral nervous system disorders through the modulation of potassium ion flux through voltage-dependent potassium channels and/or depressing or enhancing cortical and/or peripheral neuron activity, compositions containing same and methods utilizing same are disclosed. Also disclosed are modulators of voltage-dependent potassium channels, which exhibit blocking of a TRPV1 channel, and hence are useful in the treatment of TRPV1-related conditions.
公开/授权文献
- EP2203411B1 N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF 公开/授权日：2016-01-06
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