发明授权
- 专利标题： COMPOSITIONS AND METHODS OF ENHANCING IMMUNE RESPONSES TO EIMERIA
- 专利标题（中）： 增强对埃米利亚免疫反应的组合物和方法
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申请号： EP08843740.5申请日： 2008-11-03
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公开(公告)号： EP2214701B1公开(公告)日： 2016-08-03
- 发明人: BOTTJE, Walter , HARGIS, Billy , BERGHMAN, Luc , KWON, Young, Min , COLE, Kimberly , COX, Mandy , LAYTON, Sherryll , EL-ASHRAM, Saeed , BARTA, John , TELLEZ, Guillermo
- 申请人： The Board of Trustees of the University of Arkansas , The Texas A&M University System , University of Guelph
- 申请人地址： 2404 North University Avenue Little Rock, AR 72207 US
- 专利权人： The Board of Trustees of the University of Arkansas,The Texas A&M University System,University of Guelph
- 当前专利权人： The Board of Trustees of the University of Arkansas,The Texas A&M University System,University of Guelph
- 当前专利权人地址： 2404 North University Avenue Little Rock, AR 72207 US
- 代理机构： Kremer, Simon Mark
- 优先权： US984612P 20071101
- 国际公布： WO2009059298 20090507
- 主分类号： A61K39/012
- IPC分类号： A61K39/012 ; A61K38/04
摘要：
Vaccines comprising TRAP polypeptides and Salmonella enteritidis vectors comprising TRAP polypeptides are provided. The vaccines may also include a CD 154 polypeptide capable of binding to CD40. Also provided are methods of enhancing an immune response against Apicomplexan parasites and methods of reducing morbidity associated with infection with Apicomplexan parasites.
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