发明公开
- 专利标题： AGENT FOR ENHANCING ANTI-TUMOR EFFECT COMPRISING OXALIPLATIN LIPOSOME PREPARATION, AND ANTI-TUMOR AGENT COMPRISING THE LIPOSOME PREPARATION
- 专利标题（中）： 手段增强抗肿瘤效应奥沙利铂脂质体抗肿瘤药物与脂质体
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申请号： EP09706367.1申请日： 2009-01-29
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公开(公告)号： EP2246056A1公开(公告)日： 2010-11-03
- 发明人: ISHIDA, Tatsuhiro , KIWADA, Hiroshi
- 申请人： The University of Tokushima , Taiho Pharmaceutical Co., Ltd.
- 申请人地址： 2-24 Shinkura-cho Tokushima-shi Tokushima 770-8501 JP
- 专利权人： The University of Tokushima,Taiho Pharmaceutical Co., Ltd.
- 当前专利权人： The University of Tokushima,Taiho Pharmaceutical Co., Ltd.
- 当前专利权人地址： 2-24 Shinkura-cho Tokushima-shi Tokushima 770-8501 JP
- 代理机构： Vossius & Partner
- 优先权： JP2008019141 20080130; JP2008306072 20081201
- 国际公布： WO2009096487 20090806
- 主分类号： A61K31/513
- IPC分类号： A61K31/513 ; A61K9/127 ; A61K31/282 ; A61K31/4412 ; A61K31/53 ; A61K47/24 ; A61K47/34 ; A61P35/00 ; A61P43/00
摘要：
An object of the present invention is to further enhance the antitumor effect when oxaliplatin is administered in combination with a combination drug containing tegafur, gimeracil and oteracil potassium. According to the present invention, by using oxaliplatin encapsulated in a liposome preparation, combination therapy of oxaliplatin plus a combination drug containing tegafur, gimeracil and oteracil potassium, is revealed to show remarkably enhanced antitumor effect without increasing side effects.
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