发明公开
EP2252618A1 PYRAZOLO [1,5-a] PYRIMIDINES USEFUL AS JAK2 INHIBITORS
审中-公开
AS JAK2抑制剂SUITABLE [1,5-A]嘧啶类
- 专利标题： PYRAZOLO [1,5-a] PYRIMIDINES USEFUL AS JAK2 INHIBITORS
- 专利标题（中）： AS JAK2抑制剂SUITABLE [1,5-A]嘧啶类
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申请号： EP08867722.4申请日： 2008-12-18
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公开(公告)号： EP2252618A1公开(公告)日： 2010-11-24
- 发明人: LEDEBOER, Mark , STEWART, Michelle , MESSERSMITH, David , DUFFY, John , MARTINEZ-BOTELLA, Gabriel , COME, Jon , GAO, Huai , SALITURO, Francesco , MARONE, Valerie , PIERCE, Albert
- 申请人： Vertex Pharmaceuticals Incorporated
- 申请人地址： 130 Waverly Street Cambridge, MA 02139 US
- 专利权人： Vertex Pharmaceuticals Incorporated
- 当前专利权人： Vertex Pharmaceuticals Incorporated
- 当前专利权人地址： 130 Waverly Street Cambridge, MA 02139 US
- 代理机构： Coles, Andrea Birgit
- 优先权： US14824P 20071219
- 国际公布： WO2009085913 20090709
- 主分类号： C07D487/04
- IPC分类号： C07D487/04 ; A61K31/519 ; A61P35/00
摘要：
The present invention relates to compounds of formula (I) useful as selective inhibitors of JAK2 kinase. The invention also provides pharmaceutical acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various diseases, conditions or disorders. The invention also provides processes for preparing the compounds of the invention.
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