发明公开
EP2257549A1 NICOTINIC ACETYLCHOLINE RECEPTOR SUB-TYPE SELECTIVE AMIDES OF DIAZABICYCLOAL KANES
审中-公开
烟碱乙酰胆碱受体亚型选择性DIAZABICYCLOALKANAMIDE
- 专利标题： NICOTINIC ACETYLCHOLINE RECEPTOR SUB-TYPE SELECTIVE AMIDES OF DIAZABICYCLOAL KANES
- 专利标题（中）： 烟碱乙酰胆碱受体亚型选择性DIAZABICYCLOALKANAMIDE
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申请号： EP09716691.2申请日： 2009-03-04
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公开(公告)号： EP2257549A1公开(公告)日： 2010-12-08
- 发明人: AKIREDDY, Srinivisa Rao , BHATTI, Balwinder Singh , BREINING, Scott R. , HAMMOND, Philip S. , HEEMSTRA, Ronald Joseph , MAZUROV, Anatoly , MELVIN, Matt S. , MIAO, Lan , MURTHY, V. Srinivasa , STRACHAN, Jon-Paul , XIAO, Yun-De
- 申请人： Targacept Inc.
- 申请人地址： 200 East First Street, Suite 300 Winston-Salem, NC 27101 US
- 专利权人： Targacept Inc.
- 当前专利权人： Targacept Inc.
- 当前专利权人地址： 200 East First Street, Suite 300 Winston-Salem, NC 27101 US
- 代理机构： Crowhurst, Charlotte Waveney
- 优先权： US33959P 20080305
- 国际公布： WO2009111550 20090911
- 主分类号： C07D471/08
- IPC分类号： C07D471/08 ; A61K31/407 ; A61P25/00
摘要：
The present invention relates to compounds of the following formula (I) that bind to and modulate the activity of neuronal nicotinic acetylcholine receptors, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders, including those associated with dysfunction of the central nervous system (CNS).
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