发明公开
- 专利标题： Method of administering therapeutic polypeptides
- 专利标题（中）： Verfahren zur Verabreichung治疗师多肽
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申请号： EP10178264.7申请日： 2003-11-07
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公开(公告)号： EP2258392A1公开(公告)日： 2010-12-08
- 发明人: Silence, Karen , Vaeck, Mark , Van Bergen en Henegouwen, Paul P.M.P.
- 申请人： Ablynx N.V.
- 申请人地址： Technologiepark 4 9052 Zwijnaarde BE
- 专利权人： Ablynx N.V.
- 当前专利权人： Ablynx N.V.
- 当前专利权人地址： Technologiepark 4 9052 Zwijnaarde BE
- 代理机构： HOFFMANN EITLE
- 优先权： US425073P 20021108; US425063P 20021108; EP03447005 20030110; PCT/EP03/06581 20030623; PCT/EP03/07313 20030708
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C07K16/18 ; A61P11/06 ; A61P35/00 ; A61P31/16
摘要：
The invention relates to a method suitable for administering protein therapeutic molecules orally, sublingually, topically, intravenously, subcutaneously, nasally, vaginally, rectally or by inhalation so as to avoid inactivation, by using VHH polypeptides derived from Camelidae antibodies. The invention further relates to the said therapeutic molecules. The invention further a method for delivering therapeutic molecules to the interior of cells. The invention furthe relates to anti-lgE therapeutic molecules.
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