发明公开
- 专利标题: Sustained drug-releasing stent
- 专利标题(中): 支架用于连续递送药物
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申请号: EP10164082.9申请日: 2008-09-03
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公开(公告)号: EP2258414A3公开(公告)日: 2014-08-27
- 发明人: Iwata, Hiroo , Omura, Ikuo , Jin, Zhen Yu , Yamashita, Shuzo , Mochizuki, Akira
- 申请人: Japan Stent Technology Co., Ltd. , TOKAI UNIVERSITY EDUCATIONAL SYSTEM , Iwata, Hiroo
- 申请人地址: 5303, Haga, Kita-ku Okayama-shi, Okayama 701-1221 JP
- 专利权人: Japan Stent Technology Co., Ltd.,TOKAI UNIVERSITY EDUCATIONAL SYSTEM,Iwata, Hiroo
- 当前专利权人: Japan Stent Technology Co., Ltd.,TOKAI UNIVERSITY EDUCATIONAL SYSTEM,Iwata, Hiroo
- 当前专利权人地址: 5303, Haga, Kita-ku Okayama-shi, Okayama 701-1221 JP
- 代理机构: Vossius & Partner
- 优先权: JP2007228788 20070904
- 主分类号: A61L31/10
- IPC分类号: A61L31/10 ; A61L31/16
摘要:
A stent includes a stent body of a cylindrical configuration having outer and inner surfaces, a first coated layer coating at least the outer surface, and a second coated layer coating substantially completely over the first coated layer. The first coated layer is prepared of a first composition comprising a polymer and a vascular intimal hyperplasia inhibitor (preferably argatroban) of a kind, which does not inhibit proliferation of endothelial cells, the weight compositional ratio of the polymer to the inhibitor being within the range of 8 : 2 to 3 : 7. On the other hand, the second coated layer is prepared of a polymer alone or a second composition comprising a polymer and a drug, the weight compositional ratio of the drug to 80 % by weight of the polymer being less than 20 % by weight.
公开/授权文献
- EP2258414A2 Sustained drug-releasing stent 公开/授权日:2010-12-08
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